Genome Integrity: A HAT Needs a Chaperone
نویسنده
چکیده
Histone acetylation helps to maintain integrity of the yeast replisome in response to genotoxic agents. Four groups have now identified protein Rtt109p as the catalytic subunit of a novel histone H3 acetylase complex that harbors a histone chaperone subunit essential for significant activity.
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عنوان ژورنال:
- Current Biology
دوره 17 شماره
صفحات -
تاریخ انتشار 2007